Warren M. Grill

Image of Warren M. Grill

Addy Professor of Biomedical Engineering in the Edmund T. Pratt, Jr. School of Engineering

Our research is in the area of neural engineering: using engineering techniques to understand and control neural function. We work primarily on fundamental questions related to neural prostheses. Neural prostheses are a developing technology that uses electrical activation of the nervous system to restore function to individuals with neurological impairment. The long-term goal of our research program is to develop advanced neural prostheses that interface with the central nervous system (brain and spinal cord) to restore function.

Current projects include electrical stimulation for restoration of bladder function, deep brain stimulation for treatment of motor disorders, electrical stimulation for restoration of multi-joint motor function (e.g., reaching), and design of novel electrodes and waveforms for selective stimulation of the nervous system.

Appointments and Affiliations
  • Addy Professor of Biomedical Engineering in the Edmund T. Pratt, Jr. School of Engineering
  • Professor of Biomedical Engineering
  • Professor in Neurobiology
  • Professor in the Department of Electrical and Computer Engineering
Contact Information:
  • Office Location: Ciemas 1139, Durham, NC 27708
  • Office Phone: (919) 660-5276
  • Email Address: warren.grill@duke.edu
Education:

  • Ph.D. Case Western Reserve University, 1995
  • M.S. Case Western Reserve University, 1992
  • B.S. Boston University, 1989

Research Interests:

Dr. Grill’s research interests and in neural engineering and neural prostheses and include design and testing of electrodes and stimulation techniques, the electrical properties of tissues and cells, and computational neuroscience with applications in restoration of bladder function, treatment of movement disorders with deep brain stimulation, and treatment of chronic pain.

Specialties:

Neuroengineering
Neural Prosthesis

Awards, Honors, and Distinctions:

  • Outstanding Postdoc Mentor, Duke University, 2013
  • Secretarial Appointee, Department of Veterans Affairs Advisory Committee on Prosthetics and Special-Disabilities Programs, 2013
  • Elected Fellow, Biomedical Engineering Society, 2011
  • Chair, Neurotechnology Study Section, National Institutes of Health, 2010-2012
  • Capers & Marion McDonald Award for Excellence in Teaching and Research, Duke University, Pratt School of Engineering
  • Distinguished Alumni Award for Service to Profession, Boston University, 2007
  • Fellow, American Institute of Medical and Biological Engineering, 2007
  • Senior Member, Institute of Electrical & Electronic Engineers, 2006

Courses Taught:
  • BME 301L: Bioelectricity (AC or GE)
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 504: Fundamentals of Electrical Stimulation of the Nervous System (GE, EL)
  • BME 515: Neural Prosthetic Systems
  • BME 515: Neural Prosthetic Systems (GE,EL,IM)
  • BME 899: Special Readings in Biomedical Engineering
  • NEUROSCI 301L: Bioelectricity (AC or GE)
  • NEUROSCI 504: Fundamentals of Electrical Stimulation of the Nervous System (GE, EL)
  • NEUROSCI 515: Neural Prosthetic Systems
  • NEUROSCI 515: Neural Prosthetic Systems (GE,EL,IM)

Representative Publications: (More Publications)
    • Swan, BD; Grill, WM; Turner, DA, Investigation of Deep Brain Stimulation Mechanisms During Implantable Pulse Generator Replacement Surgery., Neuromodulation (2013) [10.1111/ner.12123] [abs].
    • McGee, MJ; Grill, WM, Selective co-stimulation of pudendal afferents enhances bladder activation and improves voiding efficiency., Neurourology and Urodynamics (2013) [10.1002/nau.22474] [abs].
    • Kent, AR; Grill, WM, Neural origin of evoked potentials during thalamic deep brain stimulation., Journal of Neurophysiology, vol 110 no. 4 (2013), pp. 826-843 [10.1152/jn.00074.2013] [abs].
    • Mueller, JK; Grill, WM, Model-based analysis of multiple electrode array stimulation for epiretinal visual prostheses., Journal of Neural Engineering, vol 10 no. 3 (2013) [10.1088/1741-2560/10/3/036002] [abs].
    • Kent, AR; Grill, WM, Model-based analysis and design of nerve cuff electrodes for restoring bladder function by selective stimulation of the pudendal nerve., Journal of Neural Engineering, vol 10 no. 3 (2013) [10.1088/1741-2560/10/3/036010] [abs].